Clomid (Clomiphene): What It Does and Who Uses It

Clomid (clomiphene citrate) is a common fertility drug used to trigger ovulation. If you’re not ovulating regularly, your doctor may prescribe Clomid to help you release an egg. It’s been used for decades and works by nudging your brain to make more follicle-stimulating hormones, which encourage the ovaries to produce and release eggs.

Some people also use clomiphene off-label — for example, men with low testosterone or certain hormone imbalances. But don’t start Clomid without a prescription and a clear plan from your clinician.

How to take Clomid and typical dosing

Clomid usually comes as a 50 mg tablet. A common approach is 50 mg once daily for five days, often starting on day 3, 4, or 5 of your menstrual cycle. If ovulation doesn’t happen, the doctor may increase the dose to 100 mg for the next cycle. Most providers limit treatment to about six cycles because long-term safety and benefit beyond that are limited.

Timing matters. Your clinic may ask you to track ovulation using ovulation predictor kits, ultrasound, or blood tests. That helps decide the best day for intercourse or for timed insemination. If you’re taking other fertility meds, your doctor will explain how they fit together.

Side effects, risks, and when to call your doctor

Common side effects are hot flashes, mood swings, nausea, breast tenderness, and mild headaches. Many people find these manageable. A less common but serious risk is ovarian hyperstimulation syndrome (OHSS) — signs include rapid weight gain, severe abdominal pain, vomiting, or shortness of breath. Seek medical care if that happens.

Clomid can also cause visual changes for some people. Blurry vision, flashes, or spots are red flags; stop the drug and contact your doctor right away. If you have liver disease, uncontrolled thyroid or adrenal issues, or unexplained uterine bleeding, Clomid is usually not recommended.

There’s a slightly higher chance of multiple pregnancies (twins are the most common). Your doctor will discuss that risk with you before starting treatment.

Drug interactions are uncommon but possible. Tell your clinician about prescription meds, herbal supplements, and over-the-counter drugs. Don’t combine Clomid with other fertility drugs unless your provider prescribes the combo.

Buying tips: Clomid requires a prescription in most countries. If you consider an online pharmacy, pick a licensed, reputable source and verify the prescription process. Avoid sites that sell without a prescription or offer suspiciously low prices.

Questions to ask your doctor: What dose should I start on? How will you monitor ovulation? How long should I try Clomid before switching approaches? Getting clear answers helps you stay safe and focused on results.

Clomid can be a simple, effective step toward ovulation and pregnancy when used under medical supervision. Talk openly with your provider about goals, risks, and next steps so you get a plan that fits your needs.